Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAN3 All Species: 25.76
Human Site: S196 Identified Species: 37.78
UniProt: Q58A45 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q58A45 NP_787050.4 741 82181 S196 M S L S A G S S P L H S P K I
Chimpanzee Pan troglodytes XP_001136622 741 82148 S196 M S L S A G S S P L H S P K I
Rhesus Macaque Macaca mulatta XP_001097210 741 82134 S196 M S L S A G S S P L H S P K I
Dog Lupus familis XP_543150 987 105833 S442 M S L S A G S S P L H S P K I
Cat Felis silvestris
Mouse Mus musculus Q640Q5 691 76362 A183 S T P A N N P A P Q P P S S G
Rat Rattus norvegicus XP_002724835 883 95283 S338 M S L S A G S S P L H S P K I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519591 717 78728 Y200 H T P N P A N Y L V P S S A S
Chicken Gallus gallus XP_417120 757 83269 S213 M S L S A G S S P L H S P K I
Frog Xenopus laevis NP_001128699 631 68072 G123 Y F S T S F I G L N G F G S P
Zebra Danio Brachydanio rerio XP_002666687 799 86684 S255 L A P G M S L S A G S S P L H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_728797 788 85176 P200 P I A I S G A P P N P A A A P
Honey Bee Apis mellifera XP_623553 607 67474 A99 T Y F Y L G N A V T D T V G T
Nematode Worm Caenorhab. elegans P34653 632 71182 P124 S P Q M A Q Q P P T L Q Q S A
Sea Urchin Strong. purpuratus XP_796055 760 83393 A215 F V S G S L S A G A S P L H S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P36102 679 76436 H171 I H T N A N A H S F P F P S I
Red Bread Mold Neurospora crassa Q7SDP4 656 73993 H148 I S Q N G A Q H V T Q D G G L
Conservation
Percent
Protein Identity: 100 99.8 99.7 74.4 N.A. 90.1 82.2 N.A. 80.8 78.3 58.4 68.2 N.A. 38.5 41.8 31.9 49.3
Protein Similarity: 100 100 99.8 74.7 N.A. 90.9 83 N.A. 86 84.1 64 75 N.A. 55.7 59.6 49.5 62.6
P-Site Identity: 100 100 100 100 N.A. 6.6 100 N.A. 6.6 100 0 20 N.A. 13.3 6.6 13.3 6.6
P-Site Similarity: 100 100 100 100 N.A. 26.6 100 N.A. 33.3 100 13.3 33.3 N.A. 33.3 26.6 13.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 21.7 28
Protein Similarity: N.A. N.A. N.A. N.A. 42.1 45.2
P-Site Identity: N.A. N.A. N.A. N.A. 20 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 40 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 7 7 50 13 13 19 7 7 0 7 7 13 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 7 7 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 7 7 7 0 0 7 0 0 0 7 0 13 0 0 0 % F
% Gly: 0 0 0 13 7 50 0 7 7 7 7 0 13 13 7 % G
% His: 7 7 0 0 0 0 0 13 0 0 38 0 0 7 7 % H
% Ile: 13 7 0 7 0 0 7 0 0 0 0 0 0 0 44 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 38 0 % K
% Leu: 7 0 38 0 7 7 7 0 13 38 7 0 7 7 7 % L
% Met: 38 0 0 7 7 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 19 7 13 13 0 0 13 0 0 0 0 0 % N
% Pro: 7 7 19 0 7 0 7 13 57 0 25 13 50 0 13 % P
% Gln: 0 0 13 0 0 7 13 0 0 7 7 7 7 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 13 44 13 38 19 7 44 44 7 0 13 50 13 25 13 % S
% Thr: 7 13 7 7 0 0 0 0 0 19 0 7 0 0 7 % T
% Val: 0 7 0 0 0 0 0 0 13 7 0 0 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 7 0 7 0 0 0 7 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _